ea0030oc4.1 | Oral Communications 4 | BSPED2012
Kendall Deborah
, Amin Rakesh
, Barrett Timothy
, Dimitri Paul
, Ivison Fiona
, Kibirige Mohammed
, Mathew Verghese
, Matyka Krystyna
, Govern Ann Mc
, Stirling Heather
, Tetlow Lesley
, Vail Andy
, Wales Jerry
, Wright Neil
, Clayton Peter
, Hall Catherine
Background: Childhood obesity is increasingly associated with type 2 diabetes (T2D). Metformin reduces the risk for T2D in adult obese non-diabetic patients, but the evidence in obese children and young people (CYP) is inconclusive.Design: The metformin in obese children and adolescents (MOCA) trial was a prospective, multi-centre, randomized, double-blind, placebo-controlled trial of 1.5 g metformin daily in CYP with raised fasting or post-prandial insu...